P39 A wave moving marine materials up to the biomedical field: engineering different human tissues as high added-value blue biotechnology approach

P39 A wave moving marine materials up to the biomedical field: engineering different human tissues as high added-value blue biotechnology approach

​Tiago H. Silva1and Rui L. Reis1

13B's Research Group, University Of Minho, Guimarães, PRT

Marine organisms synthesize a plethora of chemical compounds with vast biological activity. In many occasions, such compounds organize themselves in such particular architectures that the resulting structures exhibit astonishing features regarding mechanical or biological performance. Thus, marine environment has been a remarkable source of inspiration for scientists and engineers, including the ones developing innovative biomaterials to promote the regeneration of different human tissues. Besides, other functional materials are also being proposed with biomedical application. In this perspective, several examples being developed in our lab will be discussed, namely (i) squid chitosan, fucoidan and marine collagens for scaffolding and cell encapsulation; (ii) fucoidan exhibiting anti-tumor activity over breast cancer cells, depending on chemical features; (iii) dynamic collagenous tissues as inspiration for the development of functional and smart biomaterials; and (iv) marine sponges architectures as potential Naturemade scaffolds.