Enzyme development: From sequence to enzyme in 8 weeks

Thursday March 9
Parallel Session 3B: Synthetic biology – Enabling targeted and accelerated production organism development
16:10

Enzyme development: From sequence to enzyme in 8 weeks

Stuart West, Managing Director
Biocatalysts, UK

The world of enzyme discovery and development has totally changed over the past 30 years from the time that the first GMM enzymes were commercialised. Back then, enzyme discovery was all about having extensive culture collections and being able to screen for novel enzymes. This was both expensive and time-consuming. The rapid and cheap gene sequencing and synthesis machines that came out of the human genome project in combination with much faster computing power have changed this forever. Just as there is now information overload, there is also a surplus of novel enzymes sitting on DNA databases that are free and accessible to everyone. This presentation will explain how kg quantities of novel enzymes can be produced in a couple of months and for very little cost.